Friday, October 22, 2010

Seniors taking 20 pills a day

In the majority of situations no Rx interaction profiles are undertaken nor are reviews of the nutrient depletion caused by Rx. Also to be considered is a thorough review of side effects and risk of developing other conditions as a result of taking a drug.

Our Health Forensics (c) model covers these concerns as part of the health coaching we have done for 30+ years.

From a Medco Health Solutions survey of seniors 65 and older who take medications. [Note that 20% of insured seniors did not take any medication on a regular basis.]

http://patientadvocate.files.wordpress.com/2010/01/medco-study-on-pills-per-day-for-seniors.png 

Chemo Recipients Benefit from Vitamin E

In a new report of a study involving people treated with cisplatin chemotherapy and provided with daily vitamin E, good benefits were found.

Participants were randomly assigned to receive vitamin E supplementation (alpha-tocopherol 400 mg/day) or placebo. Treatment was started orally before chemotherapy and continued for 3 months after the suspension of cisplatin.

The results of our study indicate that vitamin E supplementation significantly protects against cisplatin peripheral neurotoxicity and reduces the incidence and intensity of neuropathic signs and symptoms.

Another important point is that vitamin E supplementation does not interfere with cisplatin antitumor activity.

No side effects were noted in any of the study participants.

Report published in the journal, Neurology, 2010;74(9):762-6. 47824 (5/2010)

Amish families exempt from insurance mandate

UPDATE: 25 March -  Seems as if some one else noticed this issue recently on a right wing blog.   Still no one seems to be addressing the key issue of  it being illegal to establish classes of recipients.

From Jan. 2010 -

There is an interesting premise involved in this story, and while it is interesting, why are there other similar groups denied this exemption?

Watertown Daily Times Amish families exempt from insurance mandate

Pet Peeve Rant

'Get on Board or Get Left Behind'is the subject of an email I just received, advertising CME for health professionals who are moving into a newer (although not always better) approach to mainstream medicine.

It is sort of the way I feel about the license-required medical naturopaths who ewant to control all of what is now referred to as Integrative, Complementary, or Alternative health care. And they want insurance reimbursement among other things which really serves no real purpose other than turning over your practice to Big Insurance and raising costs to "patients".

I just wonder where these people were decades ago when I was using my herbal, homeopathy, and natural medicine education while learning more in the medical field while becoming an RN and Nurse Practitioner.

They certainly put up a big defense that has just become larger as the years have gone by, and shown total disregard for others who were educated as NDs before the license-rs came along.

It would be so nice it everyone worked together and honored, respected, and supported ALL working for the best of patient care, rather than worry about who's in charge, or who's on first!

IN THIS AGE OF CONSUMER AWARENESS, it is critical for anyone who wishes to practice Anti-Aging Medicine – the fastest growing medical specialty – to have their credentials in order. The A4M offers an elite Fellowship Program in Anti-Aging, Regenerative and Functional Medicine that will give you the knowledge needed to run a successful Anti-Aging Practice.

Wednesday, October 20, 2010

Mixups Sidetrack Cancer Research

More than 100 studies utilizing cancer cells were completed using the wrong cells for the focus of the study. This may contribute to the real problem surrounding perpetuating research but never finding cancer cures.

The majority of people invloved in "races for the cures" rally have no idea where the money goes.  I think it is past time for people to demand results, not just sit passively by and think that fundraising and research organizations will meet this long over due goal.

It is also time for Big PhRMA stops pushing dangerous, unproven and ineffective drugs on mainstream medicine and often desperate patients, knowing full well their products have major problesm.

By John Gever, Senior Editor, MedPage Today
January 14, 2010

Explain to interested patients that medical research often begins with "test tube" studies of isolated cells and tissues. If they are mislabeled or contaminated, the results may send researchers off in the wrong direction and the error may not be detected until other studies are performed.

Review: Three cell lines thought to be esophageal cancer cells actually came from other tumor types, potentially misdirecting clinical trials and other studies, researchers said.

Genetic profiling revealed that the cell lines SEG-1, BIC-1, and SK-GT-5 -- believed to be esophageal adenocarcinoma cells -- were really derived from lung carcinoma, colorectal adenocarcinoma, and gastric fundus carcinoma, according to Winand N.M. Dinjens, PhD, of Erasmus University in Rotterdam, Netherlands, and colleagues.

"We have identified more than 100 scientific publications in which the contaminated cell lines . . . were used," they reported online in the Journal of the National Cancer Institute.

They pointed out that at least three ongoing research projects sponsored by the National Institutes of Health were funded on the basis of these cell lines.

Dinjens and colleagues also found two ongoing clinical trials that were based on experimental results obtained with the misidentified lines -- one testing sorafenib (Nexavar), the other evaluating an investigational telomerase inhibitor.

The authors recommended that both trials be reconsidered, as the underlying rationale is now suspect, but an editorial accompanying the report suggested that stopping the trials may not be warranted.

A total of 14 esophageal adenocarcinoma cell lines are currently in use, according to Dinjens and colleagues, and these are the foundation for nearly all experimental science in the disease, in the absence of animal models and familial cases.

It is generally recognized that many cell lines have been contaminated or mislabeled, they said.

Because the original tissues from which 13 of the 14 esophageal cancer cell lines were derived remain available, the researchers set out to authenticate the lines.

They used short tandem repeat profiling to compare genotypes of the cell lines with cells from the original tissues, supplemented by analyzing the exons and the intron-exon boundaries for the TP53 gene.

The TP53 gene is stable enough that mutations should persist through many cell divisions, and should therefore match in the cell lines and original tissues.

Dinjens and colleagues found that 10 of the 13 lines they analyzed were close genetic matches for the original tissues, despite "hundreds, perhaps thousands, of culture passages."

But for SEG-1, BIC-1, and SK-GT-5, the findings showed clear differences. Their genotypes were better matches for other tumor types.

The authors indicated that the scientist who originally derived SEG-1 and BIC-1 confirmed their results for those lines.

"Clearly, contamination occurred early during establishment of the cell lines, and all of the cultures that were distributed subsequently to different laboratories were contaminated," Dinjens and colleagues wrote.
SG-GT-5 turned out to be identical to a gastric fundus tumor line known as SG-GT-2. As with the other lines, communication with the researcher who first developed SG-GT-5 established that it must have been contaminated either at the site of origin or during early exchanges of cells with other laboratories.

"This report is a call for all scientists to authenticate their cell lines," Dinjens and colleagues concluded.

In an accompanying editorial, Robert H. Shoemaker, PhD, of the National Cancer Institute, agreed that the findings were important, but he disputed the suggestion that the two clinical trials are irretrievably compromised.

In both cases, Shoemaker indicated, there are other rationales for the therapies besides the in vitro results obtained with the disgraced cell lines.

Shoemaker also noted that the phenomenon of contaminated or mislabeled cell lines is not new.

The current study's most important impact, he wrote, "will likely be the definition of 10 esophageal adenocarcinoma tumor cell lines of proven authenticity for use in studies addressing this disease."

The study was funded from internal university sources.

No potential conflicts of interest were reported by study authors or the editorialist.

Primary source: Journal of the National Cancer Institute
Source reference: Boonstra J, et al "Verification and unmasking of widely used human esophageal adenocarcinoma cell lines" J Natl Cancer Inst 2010; DOI: 10.1093/jnci/djp499.

Additional source: Journal of the National Cancer Institute
Source reference: Shoemaker R, "Identification of Bona Fide Esophageal Adenocarcinoma Cell Lines" J Natl Cancer Inst2010; DOI: 10.1093/jnci/djp526.
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Quackwatch named quack once again

I am always amazed how mainstream media leans on every breath of what quack-doctor Stephen Barrett says or posts on his website.

Once again he seems to be in trouble in Federal Court. Soon media types just might get an idea that he is just a paid ad-man hack for status quo.

Keep up with this story

or read more here

The Lethal Science of Splenda

UPDATE: 1/20/10  Truvia complaints  

UPDATE: 1/13/10
Not only is Splenda a risk to the health of people who use it, it seems as if it is a health risk to everyone because it is not cleared by water treatment systems. Note, however, that *the science proves that sucralose is broken down in the human body* and this is not reported by the writer in the article that follows.

That Splenda you're drinking will be in our water supply for awhile
By Laura Vanderkam

WASHINGTON, D.C.—People like sucralose—the artificial sweetener marketed as Splenda—because the human body *can’t break it down* and use it. That means the substance has almost no calories and makes it a popular ingredient in everything from cookies to diet sodas. Unfortunately, it turns out that modern wastewater treatment methods don’t break down Splenda either.

That, according to Smitha Ramakrishna, 17, one of 40 finalists in the 2009 Intel Science Talent Search who’ve gathered in Washington, DC, for the final judging rounds this week, means that the sweetener can accumulate in the water supply after people excrete it, potentially harming fish and other living things.

Ramakrishna, a senior at Corona del Sol High School in Chandler, Arizona, first became interested in water issues on a trip to India when she was 12. Her parents took her to an orphanage. She was appalled by the poverty—the lack of tables and chairs for eating, for instance—but what struck her most is that these children didn’t even have access to clean water. In Arizona, despite an ongoing drought, “you turn on the tap and it’s there,” she says. “You take it for granted.”

She came home and, despite her tender years, started an organization called AWAKE, dedicated to water conservation and education. Over the years, AWAKE has helped 3,000 kids in India gain access to clean water through reverse osmosis projects and rainwater harvesting systems.

By high school, however, Ramakrishna decided she wanted to focus more on the science of clean water, and less on the policy. She tried to start doing research at Arizona State University, though since she was the first high schooler her lab had ever had—and she was under age 16—this caused much controversy. “It’s almost child labor,” she says, laughing, explaining the problem. The case went all the way up to the university president’s office. But eventually she was allowed to subject sucralose to various treatments, like bacterial digestion, typically used in wastewater treatment plants. She found that sucralose resisted most of these treatments, and was only broken down into biodegradable molecules with extensive time and concentration of titanium oxide and ultraviolet light. Since few plants use these methods, that means almost all the sucralose people eat or drink winds up in the ecosystem.

It’s too soon yet to say what that will cause. Preliminary studies, Ramakrishna says, suggests that sucralose might poison fish in large enough concentrations. She plans to study this question more in college, potentially at A.S.U., where she continues to work—as do more than 10 high school students, now that she’s broken the barrier. “It’s opened a whole new door,” she says.


Originally posted 12/16/09 (2/52,000 in AOL search): Studies have shown that sucralose can:
* Cause the thymus to shrink by as much as 40% (the thymus is your immune powerhouse - it produces T cells)

* Cause enlargement of the liver and kidneys

* Reduce growth rate as much as 20%

* Cause enlargement of the large bowel area

* Reduce the amount of good bacteria in the intestines by 50%

* Increase the pH level in the intestines (a risk factor for colon cancer)

* Contribute to weight gain

* Cause aborted pregnancy low fetal body weight

* Reduce red blood cell count

Particular warning to diabetics: Researchers found that diabetic patients using sucralose showed a statistically significant increase in glycosylated hemoglobin, a marker that is used to assess glycemic control in diabetic patients. According to the FDA, sucralose "increases in glycosolation in hemoglobin imply lessening of control of diabetes."
Here's a quote from another article - Among the results in the study by Drs. Mohamed B. Abou-Donia, Eman M. El-Masry, Ali A. Abdel-Rahman, Roger E. McLendon and Susan S. Schiffman is evidence that, in the animals studied, Splenda reduces the amount of good bacteria in the intestines by 50%, increases the pH level in the intestines, contributes to increases in body weight and affects the P-glycoprotein (P-gp) in the body in such a way that crucial health-related drugs could be rejected. Turner noted that the P-gp effect "could result in crucial medications used in chemotherapy for cancer patients, AIDS treatment and drugs for heart conditions being shunted back into the intestines rather than being absorbed by the body as intended."

Even limited use of diet soda is known to damage kidney function
"Two or more servings per day of artificially sweetened soda and faster kidney function decline; no relation between sugar-sweetened beverages and kidney function decline was noted.” Moreover, this association persisted even when the researchers accounted for age, obesity, high blood pressure, cardiovascular disease, physical activity, calorie intake, diabetes and cigarette smoking. Clearly, artificially sweetened sodas are detrimental to kidney health."
Other studies have shown it is linked to cancer and has led to kidney calcification.

There are 35 articles with important information about sucralose and aspartame as well as toxicity of new so-called "natural" sweeteners you can read in Natural Health News.

We suggest using safe sweeteners like "Just Like Sugar".  For more information look for their logo in the right hand column of our BLOG.  Pure extract of stevia is also safe, and can be ordered from us.  You must make sure that any stevia product you purchase is pure, not combined with other harmful ingredients.

And from 2006 -
KOMO TV - Seattle, Herb Weisbaum, Published April 9, 2006

SEATTLE - An investigation by the Environmental Working Group, a well-respected consumer organization, finds high levels of benzene contamination in diet soda.

Benzene is a known cancer causer, something you do not want in your food.

The EWG based its report on data collected by the Food and Drug Administration from 1995 through 2001. It showed that 79 percent of the diet soda samples tested during this six-year period "were contaminated with benzene at levels above the federal limit for benzene in tap water."

The average benzene level found in the diet soda was 19 parts per billion, nearly 4 times higher than the tap water standard which is 5 parts per billion. No brands were identified by the FDA, so I can't tell you which pop they tested.

The Environmental Working Group is not suggesting people stop drinking soft drinks. It does want the FDA to make its test reports public and to take action when manufacturers violate the established safety standards.

The EWG did criticize the FDA for making statements that the benzene levels it found were "insignificant" and "do not suggest a safety concern."

The consumer group says benzene is more likely to be formed when soda pop is stored at warm temperatures for long periods of time.
Read more...