Showing posts with label Seroquel. Show all posts
Showing posts with label Seroquel. Show all posts

Friday, March 4, 2011

Drug Firms Mislead Public

Cherry picking data is one ploy used to deliberately mis-inform the public, regulators and providers who ultimately prescribe the pharmaceuticals.

Cherry picking is where you report only flattering data, and ignore or bury data you don't like.

For example:
Drug firms hiding negative research are unfit to experiment on people
Another pharmaceutical giant has settled a big compensation claim. So why are they allowed to go on misleading the public?
But in among all these important negative findings, on a few measures of "cognitive functioning" – an attention task, a verbal memory test – Seroquel did better. This finding alone was published in a research paper in 2002. AstraZeneca kept quiet about the fact that patients on Seroquel had worse outcomes for schizophrenia. The research paper went on to become a highly influential piece of work, cited by more than 100 academic research papers. Many researchers can only dream of publishing such a well cited piece of work."
Read Ben Goldacres's complete article

Thursday, September 2, 2010

Veterans, Psych Drugs, and Deaths

Recently reported in Marine Corps Times and other media venues including Preventive Psychiatry E-Newsletter, it has been noted that psychotropic drug-induced sudden deaths are increasing in Iraq War Veterans.

Most of the newer psych drugs are fluoride based and are known to have cardiac effects among the many problems they cause.

Other over looked problems may be from depleted uranium exposure.

If you suppress respiratory function enough you will impact heart function because of low oxygen levels. Old studies showed that low O2 levels in the blood caused more deaths at 4 AM and that often there was evidence of cardiac arrythmia.

Read complete article
Interactions: Combined Seroquel, Klonopin, Paxil
clonazepam ↔ paroxetine
Applies to: Klonopin (clonazepam), Paxil (paroxetine)

MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

clonazepam ↔ quetiapine
Applies to: Klonopin (clonazepam), Seroquel (quetiapine)

MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

paroxetine ↔ quetiapine
Applies to: Paxil (paroxetine), Seroquel (quetiapine)

MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

MANAGEMENT: During concomitant use of these three drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression . Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.