Showing posts with label Elder care. Show all posts
Showing posts with label Elder care. Show all posts

Tuesday, November 9, 2010

Call to end exclusion of elderly from drug trials

This news story caught my eye because I have become concerned about this very issue over the past six or seven years. In my way of thinking it is important to set up specific drug trials not just for Elders but for children and women too.

In 2003 my mother suffered a closed head injury, and as a result of her fall and the TBI she developed expressive aphasia.

Expressive aphasia is condition  and an acquired disorder of language due to brain damage. Most aphasias and related disorders are due to stroke, head injury, cerebral tumors, or degenerative diseases.  People may lose the ability to produce speech, to comprehend speech, to repeat, and to hear and read words in many nuanced ways. Language difficulties can also be affected by pharmaceutical drugs often over used in faculties that care for Elders.

Speech and language therapy is the mainstay of care for people with with aphasia. The timing and nature of the interventions for aphasia vary widely. Blinded studies are limited, and recovery of many degrees is expected.  Studies also indicate that speech and language therapy does improve clinical outcomes in aphasia, but individualized programs are important. 

The potential for functional recovery from primarily expressive aphasia after stroke is excellent. A neurologist should be key in evaluation and care, as well as speech therapy.

After her injury, my mother was placed in a 5 Star facility in Naples, Florida.  She was loaded up with an over abundance of psychotropic drugs, including  Zyprexa, yet did not have a neurologist or speech therapy prescribed.

Zyprexa is questionable for the elderly, especially for use in elderly women, and it can precipitate diabetes.  The case in point is that regardless of the number of drugs prescribed, and failure of the center to evaluate the drugs for interaction, no one except me questioned the use of this drug in my mother's care.  Zyprexa has an unusually difficult time being excreted by older women and as a result has a longer half-life.

Another drug being given to my mother, not prescribed by a neurologist, was Neurontin, and it is implicated in the development of impaired speech. And yet another one of the several SSRIs perscribed has a known side effect of suicidal thinking.  My mother tried to jump out of a window.  The outcome: more drugs to sedate her further.

The house psychiatrist diagnosed my mother as depressed.  Yet when I asked how he diagnosed her with the aphasia, he could not answer.  He just prescribed more drugs.

I contacted a colleague in the pharmaceutical research section dealing with psychotropic durgs at the FDA for an opinion on the list of drugs prescribed to my mother.  He was shocked, and especially noted the severe issues indicated by the drug interaction profile.

The care center supplying pharmacy never conducted a thorough interaction profile. 
The attending GP, a whining DO from a near by town, most likely interested in the Medicare reimbursement more than my mother's condition, whined to my brother after I talked with him, saying he did not like the questions I was asking.

The director of nursing threatened forced relocation if my mother was taken off any of the drugs.  Since the bill went to Medicare I am sure reimbursement was more the concern than my mother's well being.  And of course there is the issue of staff convenience.

Well, my mother died last summer.  She won't be forced now to take any more drugs, but for six years which must have been agonizing for her, she was over drugged and could not communicate.

My little brother, who held POA, a player in the insurance/finance business, made absolutely no effort to see that my mother was taken to a nationally recognized neurologist in Naples.  Nor would acknowledge my concerns over the drugs and her treatment.  He failed to get her even the most clearly established care for  the aphasia, but was concerned over the cost of the drugs.

He also failed to tell the care center that my mother had a daughter, and didn't make any effort to contact me about this incident until three months after it happened.
Read the complete areticle here - http://news.bbc.co.uk/2/hi/health/8487509.stm

Wednesday, September 22, 2010

Too many Drugs, Too High Doses: Too Much for Elders

My mother was an Elder.  She was over-drugged for a number of years in a Florida Five-Star facility and the threat of forced relocation was held over her POA if she wasn't drugged.  I'm sure Medicare fraud is an issue here but needless to say, she was not alone.

I'm also wondering why doctors can't look at magnesium and B complex before drugs for hypertension, or even other natural approaches.
Old heart patients 'over-drugged'

Elderly patients are being treated too aggressively for high blood pressure, researchers claim.

They say the "oldest olds", meaning patients aged 80 plus, are being given too many drugs and in too large doses, which may do them more harm than good.

The Cochrane scientists who looked at the available data say doctors can set their targets lower for octogenarians.  This makes good economic and clinical sense given the expanding elderly population, they told bmj.com.

But doctors said high blood pressure is largely under-recognised and under-treated in the UK.

Growing need

Experts say the "oldest olds" are the fastest growing sector of the world's population.

According to latest estimates, the UK population of 85-year-olds will go up by a third by 2020.

And more than half of these will need treatment for high blood pressure, the British Medical Journal reports.

“ Most sensible GPs - which most GPs are - take a pretty cautious view to doling out drugs to old people. ”  Professor Peter Weissberg British Heart Foundation
But head of the Cochrane research group, Dr James Wright, says clinicians should change what they are presently doing and move towards a more conservative approach for the over 80s.

"I have done so with my patients," he said.

'Less better'

His review of existing studies, including data from two new trials which looked specifically at the effect of blood pressure drugs in this age group, found little evidence that aggressive treatment saves more lives.

Although fewer patients died of strokes, the total number of deaths from all causes was unchanged.

The only trial that found a significant reduction in overall mortality was the most conservative in terms of number of drugs and dose of drugs allowed.

Based on the findings, he suggests a target blood pressure of 150/80 mmHg is more sensible, and says doctors should not be worried if only half of their most elderly patients achieve it.

Professor Peter Weissberg, of the British Heart Foundation, said: "Most sensible GPs - which most GPs are - take a pretty cautious view to doling out drugs to old people.

"Hypertension is still largely under-treated. By and large, in the UK population, half of people with high blood pressure are not identified."

Story from BBC NEWS: http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/8426199.stm
Published: 2009/12/23 © BBC MMIX